Selected Publications

Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension.                                                                                 Nishida K, Brune KA, Putcha N, Mandke P, O'Neal WK, Shade D, Srivastava V, Wang M, Lam H, An SS, Drummond MB, Hansel NN, Robinson DN, Sidhaye VK.  Am J Physiol Lung Cell Mol Physiol. 2017 Jun 22:ajplung.00074.2017. doi: 10.1152/ajplung.00074.2017. [Epub ahead of print]  PMID: 2864226

Gestational Exposure to Sidestream (Secondhand) Cigarette Smoke Promotes Transgenerational Epigenetic Transmission of Exacerbated Allergic Asthma and Bronchopulmonary Dysplasia.                                                                                                                                                                                                                             Singh SP, Chand HS, Langley RJ, Mishra N, Barrett T, Rudolph K, Tellez C, Filipczak PT, Belinsky S, Saeed AI, Sheybani A, Exil V, Agarwal H, Sidhaye VK, Sussan T, Biswal S, Sopori M.  J Immunol. 2017 May 15;198(10):3815-3822. doi: 10.4049/jimmunol.1700014. Epub 2017 Apr 5.PMID: 28381639

HIV Impairs Lung Epithelial Integrity and Enters the Epithelium to Promote Chronic Lung Inflammation                                                                                      Brune KA, Ferreira F, Mandke P, Chau E, Aggarwal NR, et al. (2016)  PLOS ONE 11(3): e0149679. doi: 10.1371/journal.pone.0149679

Pulmonary epithelial barrier function- some new players and mechanisms                                                                                                                                                        Kieran Brune, James Andrew Frank, Andreas Schwingshackl, James H.Finigan, Venkataramana K. Sidhaye. American Journal of Physiology - Lung Cellular and Molecular Physiology Jan 2015, ajplung.00309.2014; DOI:10.1152/ajplung.00309.2014

Nrf2 reduces allergic asthma in mice through enhanced airway epithelial cytoprotective function.                                                                                                  Sussan TE, Gajghate S, Chatterjee S, Mandke P, McCormick S, Sudini K, Kumar S, Breysse PN, Diette GB, Sidhaye VK, Biswal S.  Am J Physiol Lung Cell Mol Physiol. 2015 Jul 1;309(1):L27-36. doi: 10.1152/ajplung.00398.2014. Epub 2015 May 8.  PMID: 25957295 Free PMC Articl

Aquaporin 5 regulates cigarette smoke induced emphysema by modulating barrier and immune properties of the epithelium                                      Aggarwal NR, Chau E, Garibaldi BT, et al. Tissue Barriers. 2013;1(4):e25248. doi:10.4161/tisb.25248.

A novel role for aquaporin-5 in enhancing microtubule polymerization                                                                                                                                                            Sidhaye VK, Chau E, Srivastava V, Sirimalle S, Balabhadrapatruni C, Aggarwal NR, D’Alessio FR, Robinson DN, King LS.  .  PLoS One 2012; 7(6): e38717. PMCID:PMC3371026

Aquaporin 5 polymorphisms and rate of lung function decline in chronic obstructive pulmonary disease.                                                                                        Hansel NN, Sidhaye V, Rafaels NM, Gao L, Gao P, Williams R, Connett JE, Beaty TH, Mathias RA, Wise RA, King LS, Barnes KC.  PLoS One. 2010 Dec 3;5(12):e14226. doi: 10.1371/journal.pone.0014226. PMID: 21151978 Free PMC Articl

Shear stress regulates aquaporin-5 and airway epithelial barrier function                                                                                                                                                        Sidhaye VK, Schweitzer KS, Caterina MJ, Shimoda L, King LS.  PNAS. 2008; 105(9):3345-50.  PMCID: PMC2265191.

Septin-2 mediates airway epithelial barrier function in physiologic and pathologic conditions                                                                                                            Sidhaye VK, Chau E, Breysse PN, King LS. American Journal of Respiratory Cell and Molecular Biology. Am J Respir Cell Mol Biol. 2011; 45(1): 120-6. PMCID:PMC3145065